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FBXL10 Antibody (monoclonal) (M09)

Mouse monoclonal antibody raised against a partial recombinant FBXL10.

     
  • IF - FBXL10 Antibody (monoclonal) (M09) AT2011a
    Immunofluorescence of monoclonal antibody to FBXL10 on HeLa cell. [antibody concentration 10 ug/ml]
    detail
  • WB - FBXL10 Antibody (monoclonal) (M09) AT2011a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
    detail
  • E - FBXL10 Antibody (monoclonal) (M09) AT2011a
    Detection limit for recombinant GST tagged FBXL10 is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession Q8NHM5
Other Accession NM_032590
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 5G1
Calculated MW 152615 Da
Additional Information
Gene ID 84678
Other Names Lysine-specific demethylase 2B, CXXC-type zinc finger protein 2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, JmjC domain-containing histone demethylation protein 1B, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Protein JEMMA, Protein-containing CXXC domain 2, [Histone-H3]-lysine-36 demethylase 1B, KDM2B, CXXC2, FBL10, FBXL10, JHDM1B, PCCX2
Target/Specificity FBXL10 (NP_115979, 457 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFBXL10 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
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Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

References

1.JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes.Frescas D, Guardavaccaro D, Bassermann F, Koyama-Nasu R, Pagano M.Nature. 2007 Nov 8;450(7167):309-13.

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$ 350.00
Cat# AT2011a
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