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FCGR2B Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant FCGR2B.

     
  • WB - FCGR2B Antibody (monoclonal) (M01) AT2027a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
    detail
  • WB - FCGR2B Antibody (monoclonal) (M01) AT2027a
    FCGR2B monoclonal antibody (M01), clone 2E10 Western Blot analysis of FCGR2B expression in K-562 ( (Cat # AT2027a )
    detail
  • WB - FCGR2B Antibody (monoclonal) (M01) AT2027a
    Western Blot analysis of FCGR2B expression in transfected 293T cell line by FCGR2B monoclonal antibody (M01), clone 2E10.

    Lane 1: FCGR2B transfected lysate(34 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • IHC - FCGR2B Antibody (monoclonal) (M01) AT2027a
    Immunoperoxidase of monoclonal antibody to FCGR2B on formalin-fixed paraffin-embedded human placenta. [antibody concentration 6 ug/ml]
    detail
  • E - FCGR2B Antibody (monoclonal) (M01) AT2027a
    Detection limit for recombinant GST tagged FCGR2B is 0.3 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession P31994
Other Accession BC031992
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2E11
Calculated MW 34044 Da
Additional Information
Gene ID 2213
Other Names Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD32, FCGR2B, CD32, FCG2, IGFR2
Target/Specificity FCGR2B (AAH31992, 45 a.a. ~ 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFCGR2B Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

References

Dengue hemorrhagic fever is associated with polymorphisms in JAK1. Silva LK, et al. Eur J Hum Genet, 2010 Jun 30. PMID 20588308.The role of Fc gamma receptors polymorphisms in bullous pemphigoid. Guilabert A, et al. J Am Acad Dermatol, 2010 Jul. PMID 20542180.Copy number, linkage disequilibrium and disease association in the FCGR locus. Niederer HA, et al. Hum Mol Genet, 2010 Aug 15. PMID 20508037.An FcgammaRIIb transmembrane polymorphism in Chinese ITP patients. Xu J, et al. Platelets, 2010. PMID 20507212.SNPs of Fc-gamma receptor genes and chronic periodontitis. Chai L, et al. J Dent Res, 2010 Jul. PMID 20439936.

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$ 350.00
Cat# AT2027a
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Availability: 7-10 days
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