FHL1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant FHL1.
|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||36263 Da|
|Other Names||Four and a half LIM domains protein 1, FHL-1, Skeletal muscle LIM-protein 1, SLIM, SLIM-1, FHL1, SLIM1|
|Target/Specificity||FHL1 (NP_001440, 23 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||FHL1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
1.Carbonic Anhydrase III and Four-and-a-Half LIM Protein 1 are preferentially oxidized with muscle unloading.Chen CN, Ferrington DA, Thompson LV.J Appl Physiol. 2008 Nov;105(5):1554-61. Epub 2008 Aug 28.
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