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FKBP10 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant FKBP10.

     
  • WB - FKBP10 Antibody (monoclonal) (M01) AT2054a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.08 KDa) .
    detail
  • WB - FKBP10 Antibody (monoclonal) (M01) AT2054a
    FKBP10 monoclonal antibody (M01), clone 1C6 Western Blot analysis of FKBP10 expression in HeLa ( (Cat # AT2054a )
    detail
  • E - FKBP10 Antibody (monoclonal) (M01) AT2054a
    Detection limit for recombinant GST tagged FKBP10 is 1 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q96AY3
Other Accession NM_021939
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1C6
Calculated MW 64245 Da
Additional Information
Gene ID 60681
Other Names Peptidyl-prolyl cis-trans isomerase FKBP10, PPIase FKBP10, 65 kDa FK506-binding protein, 65 kDa FKBP, FKBP-65, FK506-binding protein 10, FKBP-10, Immunophilin FKBP65, Rotamase, FKBP10, FKBP65
Target/Specificity FKBP10 (NP_068758, 377 a.a. ~ 470 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFKBP10 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.

References

Mutations in the gene encoding the RER protein FKBP65 cause autosomal-recessive osteogenesis imperfecta. Alanay Y, et al. Am J Hum Genet, 2010 Apr 9. PMID 20362275.Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen JM, et al. Cell, 2009 Jul 10. PMID 19596235.The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens. Ishikawa Y, et al. J Biol Chem, 2008 Nov 14. PMID 18786928.Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC). Foster LJ, et al. J Proteome Res, 2006 Jan. PMID 16396496.Developmental regulation and coordinate reexpression of FKBP65 with extracellular matrix proteins after lung injury suggest a specialized function for this endoplasmic reticulum immunophilin. Patterson CE, et al. Cell Stress Chaperones, 2005 Winter. PMID 16333983.

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$ 350.00
Cat# AT2054a
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Availability: 7-10 days
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