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FUBP1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant FUBP1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q96AE4 |
| Other Accession | NM_003902 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3H4 |
| Calculated MW | 67560 Da |
| Gene ID | 8880 |
|---|---|
| Other Names | Far upstream element-binding protein 1, FBP, FUSE-binding protein 1, DNA helicase V, hDH V, FUBP1 |
| Target/Specificity | FUBP1 (NP_003893, 27 a.a. ~ 136 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | FUBP1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.
References
Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR. Hsiao HH, et al. Biochemistry, 2010 Jun 8. PMID 20420426.Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth. Rabenhorst U, et al. Hepatology, 2009 Oct. PMID 19637194.Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells. Malz M, et al. Hepatology, 2009 Oct. PMID 19585652.Far upstream element-binding protein-1, a novel caspase substrate, acts as a cross-talker between apoptosis and the c-myc oncogene. Jang M, et al. Oncogene, 2009 Mar 26. PMID 19219071.Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. Martins-de-Souza D, et al. Eur Arch Psychiatry Clin Neurosci, 2009 Apr. PMID 19165527.
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