FUT2 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant FUT2.
|Calculated MW||39017 Da|
|Other Names||Galactoside 2-alpha-L-fucosyltransferase 2, Alpha(1, 2)FT 2, Fucosyltransferase 2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, SE2, Secretor blood group alpha-2-fucosyltransferase, Secretor factor, Se, FUT2, SEC2|
|Target/Specificity||FUT2 (NP_000502, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||FUT2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene.
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. McGovern DP, et al. Hum Mol Genet, 2010 Sep 1. PMID 20570966.Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project. Cross DS, et al. BMC Genet, 2010 Jun 17. PMID 20565774.[Analysis of alpha-1,2-fucosyltransferase gene mutations in a Chinese family with para-Bombay phenotype] Xu XG, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2010 Jun. PMID 20533259.Polymorphisms of Lewis and Secretor genes are related to breast cancer and metastasis in axillary lymph nodes. Teresa DB, et al. Tumour Biol, 2010 Jun 1. PMID 20514537.The relationship between Lewis/Secretor genotypes and serum carbohydrate antigen 19-9 levels in a Korean population. Park HD, et al. Korean J Lab Med, 2010 Feb. PMID 20197723.
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