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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   FXR1 Antibody (monoclonal) (M01)   

FXR1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant FXR1.

  • WB - FXR1 Antibody (monoclonal) (M01) AT2127a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - FXR1 Antibody (monoclonal) (M01) AT2127a
    Western Blot analysis of FXR1 expression in transfected 293T cell line by FXR1 monoclonal antibody (M01), clone 2G11.

    Lane 1: FXR1 transfected lysate(61 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - FXR1 Antibody (monoclonal) (M01) AT2127a
    Immunoperoxidase of monoclonal antibody to FXR1 on formalin-fixed paraffin-embedded human colon adenocarcinoma. [antibody concentration 3 ug/ml]
  • E - FXR1 Antibody (monoclonal) (M01) AT2127a
    Detection limit for recombinant GST tagged FXR1 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51114
Other Accession BC028983
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 2G11
Calculated MW 69721 Da
Additional Information
Gene ID 8087
Other Names Fragile X mental retardation syndrome-related protein 1, hFXR1p, FXR1
Target/Specificity FXR1 (AAH28983, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFXR1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.


Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. International Schizophrenia Consortium, et al. Nature, 2009 Aug 6. PMID 19571811.Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Darnell JC, et al. Hum Mol Genet, 2009 Sep 1. PMID 19487368.Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients. Davidovic L, et al. J Med Genet, 2008 Oct. PMID 18628314.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Vasudevan S, et al. Cell, 2007 Mar 23. PMID 17382880.

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$ 315.00
Cat# AT2127a
(40 western blots)
Availability: 7-10 days
Bulk Size
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