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FZR1 Antibody (monoclonal) (M09)
Mouse monoclonal antibody raised against a partial recombinant FZR1.
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UM11 |
| Other Accession | NM_016263 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3.0E+12 |
| Calculated MW | 55179 Da |
| Gene ID | 51343 |
|---|---|
| Other Names | Fizzy-related protein homolog, Fzr, CDC20-like protein 1, Cdh1/Hct1 homolog, hCDH1, FZR1, CDH1, FYR, FZR, KIAA1242 |
| Target/Specificity | FZR1 (NP_057347.2, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | FZR1 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation. Naoe H, et al. Mol Cell Biol, 2010 Aug. PMID 20530197.Centrosome-related genes, genetic variation, and risk of breast cancer. Olson JE, et al. Breast Cancer Res Treat, 2010 May 28. PMID 20508983.Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis. Sigl R, et al. J Cell Sci, 2009 Nov 15. PMID 19861496.The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Bassermann F, et al. Cell, 2008 Jul 25. PMID 18662541.Dissection of the APCCdh1-Skp2 cascade in breast cancer. Fujita T, et al. Clin Cancer Res, 2008 Apr 1. PMID 18381934.
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