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GABBR1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant GABBR1.

  • WB - GABBR1 Antibody (monoclonal) (M01) AT2138a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - GABBR1 Antibody (monoclonal) (M01) AT2138a
    GABBR1 monoclonal antibody (M01), clone 2D7 Western Blot analysis of GABBR1 expression in IMR-32 ( (Cat # AT2138a )
  • WB - GABBR1 Antibody (monoclonal) (M01) AT2138a
    Western Blot analysis of GABBR1 expression in transfected 293T cell line by GABBR1 monoclonal antibody (M01), clone 2D7.

    Lane 1: GABBR1 transfected lysate(95 KDa).
    Lane 2: Non-transfected lysate.
  • IF - GABBR1 Antibody (monoclonal) (M01) AT2138a
    Immunofluorescence of monoclonal antibody to GABBR1 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - GABBR1 Antibody (monoclonal) (M01) AT2138a
    Detection limit for recombinant GST tagged GABBR1 is approximately 0.3ng/ml as a capture antibody.
  • WB - GABBR1 Antibody (monoclonal) (M01) AT2138a
    Western blot analysis of GABBR1 over-expressed 293 cell line, cotransfected with GABBR1 Validated Chimera RNAi ( (Cat # AT2138a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBS5
Other Accession BC050532
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2D7
Calculated MW 108320 Da
Additional Information
Gene ID 2550
Other Names Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, GABBR1, GPRC3A
Target/Specificity GABBR1 (AAH50532, 52 a.a. ~ 151 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGABBR1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants.


1.Conjoint occurrence of GABAB receptor antibodies in Lambert-Eaton myasthenic syndrome with antibodies to the voltage gated calcium channel.Onugoren MD, Rauschka H, Bien CGJ Neuroimmunol. 2014 May 29. pii: S0165-5728(14)00153-2. doi: 10.1016/j.jneuroim.2014.05.011.2.CORTICAL STIMULATION CAUSES LONG-TERM CHANGES IN H-REFLEXES AND SPINAL MOTONEURON GABA RECEPTORS.Wang Y, Chen Y, Chen L, Wolpaw JR, Chen XY.J Neurophysiol. 2012 Aug 29.3.Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.Tse KP, Su WH, Chang KP, Tsang NM, Yu CJ, Tang P, See LC, Hsueh C, Yang ML, Hao SP, Li HY, Wang MH, Liao LP, Chen LC, Lin SR, Jorgensen TJ, Chang YS, Shugart YY.Am J Hum Genet. 2009 Aug;85(2):194-203. Epub 2009 Aug 6.

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$ 315.00
Cat# AT2138a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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