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GAD1 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full length recombinant GAD1.

  • WB - GAD1 Antibody (monoclonal) (M02) AT2144a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (91.08 KDa) .
  • WB - GAD1 Antibody (monoclonal) (M02) AT2144a
    Western Blot analysis of GAD1 expression in transfected 293T cell line by GAD1 monoclonal antibody (M02), clone 5E11.

    Lane 1: GAD1 transfected lysate(66.9 KDa).
    Lane 2: Non-transfected lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99259
Other Accession BC037780
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 5E12
Calculated MW 66897 Da
Additional Information
Gene ID 2571
Other Names Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD1, GAD, GAD67
Target/Specificity GAD1 (AAH37780, 1 a.a. ~ 594 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGAD1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.


Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data. Jia P, et al. Schizophr Res, 2010 Sep. PMID 20659789.Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Rua?o G, et al. Pharmacogenomics, 2010 Jul. PMID 20602615.Alcohol dependence and glutamate decarboxylase gene polymorphisms in an Italian male population. Terranova C, et al. Alcohol, 2010 Aug. PMID 20598486.Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT. Marenco S, et al. Neuropsychopharmacology, 2010 Jul. PMID 20357758.

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$ 315.00
Cat# AT2144a
(40 western blots)
Availability: 7-10 days
Bulk Size
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