GDF7 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant GDF7.
|Calculated MW||46950 Da|
|Other Names||Growth/differentiation factor 7, GDF-7, GDF7|
|Target/Specificity||GDF7 (NP_878248, 361 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||GDF7 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.
An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Effects of cartilage-derived morphogenetic protein-3 on the expression of chondrogenic and osteoblastic markers in the pluripotent mesenchymal C3H10T1/2 cell line. Yeh LC, et al. Growth Factors, 2010 Apr. PMID 20102312.Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses. Mazerbourg S, et al. J Biol Chem, 2005 Sep 16. PMID 16049014.A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons. Butler SJ, et al. Neuron, 2003 May 8. PMID 12741987.
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