GKN1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant GKN1.
|Application ||WB, E|
|Calculated MW||21999 Da|
|Other Names||Gastrokine-1, 18 kDa antrum mucosa protein, AMP-18, Protein CA11, GKN1, AMP18, CA11|
|Target/Specificity||GKN1 (AAH59778, 21 a.a. ~ 185 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||GKN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.
1.Helicobacter pylori infection and administration of non-steroidal anti-inflammatory drugs down-regulate the expression of gastrokine-1 in gastric mucosa.Mao W, Chen J, Peng TL, Yin XF, Chen LZ, Chen MH.Turk J Gastroenterol. 2012 Jun;23(3):212-9.2.Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis.Mao W, Chen J, Peng TL, Yin XF, Chen LZ, Chen MH.J Exp Clin Cancer Res. 2012 May 23;31:49. doi: 10.1186/1756-9966-31-49.3.Characterization of the Human Gastric Fluid Proteome Reveals Distinct pH-Dependent Protein Profiles: Implications for Biomarker Studies.Kam SY, Hennessy T, Chua SC, Gan CS, Philp R, Hon KK, Lai L, Chan WH, Ong HS, Wong WK, Lim KH, Ling KL, Tan HS, Tan MM, Ho M, Kon OL.J Proteome Res. 2011 Aug 15. [Epub ahead of print]4.Overexpression of gastrokine 1 in gastric cancer cells induces fas-mediated apoptosis.Rippa E, La Monica G, Allocca R, Romano MF, De Palma M, Arcari P.J Cell Physiol. 2010 Dec 28. [Epub ahead of print]
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