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GLMN Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant GLMN.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, IP |
|---|---|
| Primary Accession | Q92990 |
| Other Accession | BC001257 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1C12 |
| Calculated MW | 68208 Da |
| Gene ID | 11146 |
|---|---|
| Other Names | Glomulin, FK506-binding protein-associated protein, FAP, FKBP-associated protein, GLMN, FAP48, FAP68, VMGLOM |
| Target/Specificity | GLMN (AAH01257, 1 a.a. ~ 594 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | GLMN Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
References
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Arai T, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904573.Vascular malformations: localized defects in vascular morphogenesis. Brouillard P, et al. Clin Genet, 2003 May. PMID 12752563.
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