GNG3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant GNG3.
|Application ||WB, E|
|Calculated MW||8305 Da|
|Other Names||Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3, GNG3, GNGT3|
|Target/Specificity||GNG3 (AAH15563, 1 a.a. ~ 75 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||GNG3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
G proteins are heterotrimers of alpha, beta, and gamma subunits. Gamma subunits, such as GNG3, contribute to the specificity of the hundreds of receptor signaling pathways involving G proteins (Schwindinger et al., 2004 [PubMed 15314181]).
Regulation of Golgi structure and secretion by receptor-induced G protein betagamma complex translocation. Saini DK, et al. Proc Natl Acad Sci U S A, 2010 Jun 22. PMID 20534534.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Mice with deficiency of G protein gamma3 are lean and have seizures. Schwindinger WF, et al. Mol Cell Biol, 2004 Sep. PMID 15314181.Characterization of heterotrimeric G protein complexes in rice plasma membrane. Kato C, et al. Plant J, 2004 Apr. PMID 15078334.Glucagon and regulation of glucose metabolism. Jiang G, et al. Am J Physiol Endocrinol Metab, 2003 Apr. PMID 12626323.
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