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GPR154 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant GPR154.

     
  • WB - GPR154 Antibody (monoclonal) (M01) AT2245a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.46 KDa) .
    detail
  • E - GPR154 Antibody (monoclonal) (M01) AT2245a
    Detection limit for recombinant GST tagged GPR154 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6W5P4
Other Accession NM_207173
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2F5
Calculated MW 42687 Da
Additional Information
Gene ID 387129
Other Names Neuropeptide S receptor, G-protein coupled receptor 154, G-protein coupled receptor PGR14, G-protein coupled receptor for asthma susceptibility, NPSR1, GPR154, GPRA, PGR14
Target/Specificity GPR154 (NP_997056, 2 a.a. ~ 53 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGPR154 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

References

Assessment of the neuropeptide S system in anxiety disorders. Donner J, et al. Biol Psychiatry, 2010 Sep 1. PMID 20705147.A neuropeptide S receptor variant associated with overinterpretation of fear reactions: a potential neurogenetic basis for catastrophizing. Raczka KA, et al. Mol Psychiatry, 2010 Jul 13. PMID 20628342.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Neuropeptide S receptor gene - converging evidence for a role in panic disorder. Domschke K, et al. Mol Psychiatry, 2010 Jul 6. PMID 20603625.Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Schuurhof A, et al. Pediatr Pulmonol, 2010 Jun. PMID 20503287.

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$ 350.00
Cat# AT2245a
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Availability: 7-10 days
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