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HAND2 Antibody (monoclonal) (M06)

Mouse monoclonal antibody raised against a partial recombinant HAND2.

     
  • WB - HAND2 Antibody (monoclonal) (M06) AT2315a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.76 KDa) .
    detail
  • WB - HAND2 Antibody (monoclonal) (M06) AT2315a
    Western Blot analysis of HAND2 expression in transfected 293T cell line by HAND2 monoclonal antibody (M06), clone 3D5.

    Lane 1: HAND2 transfected lysate(21.6 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • WB - HAND2 Antibody (monoclonal) (M06) AT2315a
    Western blot analysis of HAND2 over-expressed 293 cell line, cotransfected with HAND2 Validated Chimera RNAi ( (Cat # AT2315a )
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P61296
Other Accession NM_021973
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3D5
Calculated MW 23666 Da
Additional Information
Gene ID 9464
Other Names Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND, HAND2, BHLHA26, DHAND
Target/Specificity HAND2 (NP_068808.1, 135 a.a. ~ 216 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsHAND2 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

References

1.Progestin-induced heart and neural crest derivatives expressed transcript 2 is associated with fibulin-1 expression in human endometrial stromal cells.Cho H, Okada H, Tsuzuki T, Nishigaki A, Yasuda K, Kanzaki H.Fertil Steril. 2012 Oct 1. pii: S0015-0282(12)02175-9. doi: 10.1016/j.fertnstert.2012.08.056.

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$ 350.00
Cat# AT2315a
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Availability: 7-10 days
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