HBZ Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full length recombinant HBZ.
|Application ||WB, IHC, E|
|Calculated MW||15637 Da|
|Other Names||Hemoglobin subunit zeta, HBAZ, Hemoglobin zeta chain, Zeta-globin, HBZ, HBZ2|
|Target/Specificity||HBZ (NP_005323, 1 a.a. ~ 81 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||HBZ Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'.
A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.Nuclear localization of HTLV-I bZIP factor (HBZ) is mediated by three distinct motifs. Hivin P, et al. J Cell Sci, 2005 Apr 1. PMID 15755797.Effect of zeta-globin substitution on the O2-transport properties of Hb S in vitro and in vivo. He Z, et al. Biochem Biophys Res Commun, 2004 Dec 24. PMID 15555579.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
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