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HDAC8 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant HDAC8.

  • WB - HDAC8 Antibody (monoclonal) (M01) AT2342a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (66.99 KDa) .
  • WB - HDAC8 Antibody (monoclonal) (M01) AT2342a
    HDAC8 monoclonal antibody (M01), clone 2F4 Western Blot analysis of HDAC8 expression in Hela S3 NE ( (Cat # AT2342a )
  • WB - HDAC8 Antibody (monoclonal) (M01) AT2342a
    Western Blot analysis of HDAC8 expression in transfected 293T cell line by HDAC8 monoclonal antibody (M01), clone 2F4.

    Lane 1: HDAC8 transfected lysate(41.8 KDa).
    Lane 2: Non-transfected lysate.
  • IF - HDAC8 Antibody (monoclonal) (M01) AT2342a
    Immunofluorescence of monoclonal antibody to HDAC8 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - HDAC8 Antibody (monoclonal) (M01) AT2342a
    Detection limit for recombinant GST tagged HDAC8 is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BY41
Other Accession BC050433
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 2F4
Calculated MW 41758 Da
Additional Information
Gene ID 55869
Other Names Histone deacetylase 8, HD8, HDAC8, HDACL1
Target/Specificity HDAC8 (AAH50433, 1 a.a. ~ 377 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsHDAC8 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function . Dowling DP, et al. Biochemistry, 2010 Jun 22. PMID 20545365.Activation and inhibition of histone deacetylase 8 by monovalent cations. Gantt SL, et al. J Biol Chem, 2010 Feb 26. PMID 20029090.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Novel structural insights into class I and II histone deacetylases. Ficner R. Curr Top Med Chem, 2009. PMID 19355988.

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$ 315.00
Cat# AT2342a
(40 western blots)
Availability: 7-10 days
Bulk Size
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