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>   home   >   Products   >   Primary Antibodies   >   HELZ Antibody (monoclonal) (M04)   

HELZ Antibody (monoclonal) (M04)

Mouse monoclonal antibody raised against a partial recombinant HELZ.

  • WB - HELZ Antibody (monoclonal) (M04) AT2349a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • E - HELZ Antibody (monoclonal) (M04) AT2349a
    Detection limit for recombinant GST tagged HELZ is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42694
Other Accession NM_014877
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1C11
Calculated MW 218970 Da
Additional Information
Other Names Probable helicase with zinc finger domain, 364-, Down-regulated in human cancers protein, HELZ, DRHC, KIAA0054
Target/Specificity HELZ (NP_055692, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsHELZ Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).


Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis. Sombekke MH, et al. Mult Scler, 2010 Jun. PMID 20378664.Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. Suzuki Y, et al. Genome Res, 2004 Sep. PMID 15342556.Large-scale characterization of HeLa cell nuclear phosphoproteins. Beausoleil SA, et al. Proc Natl Acad Sci U S A, 2004 Aug 17. PMID 15302935.SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Hamamoto R, et al. Nat Cell Biol, 2004 Aug. PMID 15235609.Down-regulation in human cancers of DRHC, a novel helicase-like gene from 17q25.1 that inhibits cell growth. Nagai H, et al. Cancer Lett, 2003 Apr 10. PMID 12691822.

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$ 315.00
Cat# AT2349a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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