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HIP1R Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant HIP1R.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75146 |
| Other Accession | NM_003959 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 3E11 |
| Calculated MW | 119388 Da |
| Gene ID | 9026 |
|---|---|
| Other Names | Huntingtin-interacting protein 1-related protein, HIP1-related protein, Huntingtin-interacting protein 12, HIP-12, HIP1R, HIP12, KIAA0655 |
| Target/Specificity | HIP1R (NP_003950, 969 a.a. ~ 1066 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | HIP1R Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.HIP1R interacts with a member of Bcl-2 family, BCL2L10, and induces BAK-dependent cell death. Kim JH, et al. Cell Physiol Biochem, 2009. PMID 19255499.Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain. Wilbur JD, et al. J Biol Chem, 2008 Nov 21. PMID 18790740.Clathrin light chains function in mannose phosphate receptor trafficking via regulation of actin assembly. Poupon V, et al. Proc Natl Acad Sci U S A, 2008 Jan 8. PMID 18165318.Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity. Parker JA, et al. J Neurosci, 2007 Oct 10. PMID 17928447.
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