HIP1R Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant HIP1R.
|Application ||WB, E|
|Calculated MW||119388 Da|
|Other Names||Huntingtin-interacting protein 1-related protein, HIP1-related protein, Huntingtin-interacting protein 12, HIP-12, HIP1R, HIP12, KIAA0655|
|Target/Specificity||HIP1R (NP_003950, 969 a.a. ~ 1066 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||HIP1R Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.HIP1R interacts with a member of Bcl-2 family, BCL2L10, and induces BAK-dependent cell death. Kim JH, et al. Cell Physiol Biochem, 2009. PMID 19255499.Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain. Wilbur JD, et al. J Biol Chem, 2008 Nov 21. PMID 18790740.Clathrin light chains function in mannose phosphate receptor trafficking via regulation of actin assembly. Poupon V, et al. Proc Natl Acad Sci U S A, 2008 Jan 8. PMID 18165318.Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity. Parker JA, et al. J Neurosci, 2007 Oct 10. PMID 17928447.
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