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HNF4A Antibody (monoclonal) (M07)

Mouse monoclonal antibody raised against a partial recombinant HNF4A.

  • WB - HNF4A Antibody (monoclonal) (M07) AT2395a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - HNF4A Antibody (monoclonal) (M07) AT2395a
    HNF4A monoclonal antibody (M07), clone 3C6 Western Blot analysis of HNF4A expression in HepG2 ( (Cat # AT2395a )
  • WB - HNF4A Antibody (monoclonal) (M07) AT2395a
    HNF4A monoclonal antibody (M07), clone 3C6. Western Blot analysis of HNF4A expression in A-431 ( (Cat # AT2395a )
  • IF - HNF4A Antibody (monoclonal) (M07) AT2395a
    Immunofluorescence of monoclonal antibody to HNF4A on HeLa cell. [antibody concentration 10 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P41235
Other Accession NM_000457
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3C6
Calculated MW 52785 Da
Additional Information
Gene ID 3172
Other Names Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4, HNF4A, HNF4, NR2A1, TCF14
Target/Specificity HNF4A (NP_000448, 324 a.a. ~ 423 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsHNF4A Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.


COMMON VARIANTS IN 40 GENES ASSESSED FOR DIABETES INCIDENCE AND RESPONSE TO METFORMIN AND LIFESTYLE INTERVENTIONS IN THE DIABETES PREVENTION PROGRAM. Jablonski KA, et al. Diabetes, 2010 Aug 3. PMID 20682687.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Variants in hepatocyte nuclear factor 4alpha gene promoter region and type 2 diabetes risk in Chinese. Chen Z, et al. Exp Biol Med (Maywood), 2010 Jul. PMID 20558840.The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes. de Boussac H, et al. J Biol Chem, 2010 Jul 23. PMID 20463007.Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism. Ruchat SM, et al. Ann Med, 2010 Apr. PMID 20384434.

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$ 315.00
Cat# AT2395a
(40 western blots)
Availability: 7-10 days
Bulk Size
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