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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HOXD8 Antibody (monoclonal) (M03)   

HOXD8 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant HOXD8.

  • WB - HOXD8 Antibody (monoclonal) (M03) AT2430a
    HOXD8 monoclonal antibody (M03), clone 5E11 Western Blot analysis of HOXD8 expression in HepG2 ( Cat # L019V1 ).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13378
Other Accession NM_019558
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 5E12
Calculated MW 31911 Da
Additional Information
Gene ID 3234
Other Names Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-54, HOXD8, HOX4E
Target/Specificity HOXD8 (NP_062458, 126 a.a. ~ 190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsHOXD8 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function.


Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot. Ester AR, et al. Am J Med Genet A, 2009 Dec. PMID 19938081.Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis. Harada K, et al. J Cell Sci, 2009 Nov 1. PMID 19825936.High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, et al. J Bone Miner Res, 2009 Dec. PMID 19453261.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.Limb malformations and the human HOX genes. Goodman FR. Am J Med Genet, 2002 Oct 15. PMID 12357469.

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$ 315.00
Cat# AT2430a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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