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HTR5A Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant HTR5A.

  • WB - HTR5A Antibody (monoclonal) (M01) AT2457a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.34 KDa) .
  • E - HTR5A Antibody (monoclonal) (M01) AT2457a
    Detection limit for recombinant GST tagged HTR5A is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P47898
Other Accession NM_024012
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 10D3
Calculated MW 40255 Da
Additional Information
Gene ID 3361
Other Names 5-hydroxytryptamine receptor 5A, 5-HT-5, 5-HT-5A, 5-HT5A, Serotonin receptor 5A, HTR5A
Target/Specificity HTR5A (NP_076917, 223 a.a. ~ 282 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsHTR5A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.


Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064.Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels. Zhang Y, et al. Physiol Genomics, 2010 Jul 7. PMID 20388841.Association study of the serotoninergic system in migraine in the Spanish population. Corominas R, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jan 5. PMID 19455600.Differences and similarities in the serotonergic diathesis for suicide attempts and mood disorders: a 22-year longitudinal gene-environment study. Brezo J, et al. Mol Psychiatry, 2010 Aug. PMID 19381154.Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. Yosifova A, et al. J Affect Disord, 2009 Sep. PMID 19328558.

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$ 315.00
Cat# AT2457a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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