ID1 Antibody (monoclonal) (M04)
Mouse monoclonal antibody raised against a full length recombinant ID1.
|Application ||WB, IF, E|
|Calculated MW||16133 Da|
|Other Names||DNA-binding protein inhibitor ID-1, Class B basic helix-loop-helix protein 24, bHLHb24, Inhibitor of DNA binding 1, Inhibitor of differentiation 1, ID1, BHLHB24, ID|
|Target/Specificity||ID1 (AAH00613.1, 1 a.a. ~ 155 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ID1 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
1.ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma.Phi JH, Choi SA, Lim SH, Lee J, Wang KC, Park SH, Kim SKBMC Cancer. 2013 Jun 15;13:291. doi: 10.1186/1471-2407-13-291.
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