IL1F9 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant IL1F9.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9NZH8 |
Other Accession | NM_019618 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG1 Kappa |
Clone Names | 8A11 |
Calculated MW | 18721 Da |
Gene ID | 56300 |
---|---|
Other Names | Interleukin-36 gamma, IL-1-related protein 2, IL-1RP2, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 9, IL-1F9, Interleukin-1 homolog 1, IL-1H1, IL36G, IL1E, IL1F9, IL1H1, IL1RP2 |
Target/Specificity | IL1F9 (NP_062564, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | IL1F9 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
References
New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.The interleukin-1 family gene polymorphisms in Korean patients with rheumatoid arthritis. Jung MY, et al. Scand J Rheumatol, 2010 May. PMID 20141484.Interleukin 1 polymorphisms in patients with ankylosing spondylitis in Korea. Kim TJ, et al. J Rheumatol, 2008 Aug. PMID 18484691.Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Hillier LW, et al. Nature, 2005 Apr 7. PMID 15815621.Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense. Vos JB, et al. Physiol Genomics, 2005 May 11. PMID 15701729.
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