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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IL1RN Antibody (monoclonal) (M01)   

IL1RN Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant IL1RN.

  • WB - IL1RN Antibody (monoclonal) (M01) AT2513a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (43.23 KDa) .
  • E - IL1RN Antibody (monoclonal) (M01) AT2513a
    Detection limit for recombinant GST tagged IL1RN is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18510
Other Accession BC009745
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names M1-B9
Calculated MW 20055 Da
Additional Information
Gene ID 3557
Other Names Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA
Target/Specificity IL1RN (AAH09745, 1 a.a. ~ 159 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsIL1RN Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.


A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868.High-density polymorphisms analysis of 23 candidate genes for association with bone mineral density. Giroux S, et al. Bone, 2010 Jul 30. PMID 20654748.[Correlation of IL-1beta-511 and IL-1RN VNTR gene polymorphism to coronary heart disease: a Meta-analysis.] Chen F, et al. Nan Fang Yi Ke Da Xue Xue Bao, 2010 Jul. PMID 20650788.Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms are not associated with premalignant gastric conditions: a combined haplotype analysis. Kupcinskas L, et al. Eur J Gastroenterol Hepatol, 2010 Oct. PMID 20631624.Interleukin-1A +4845(G>T) polymorphism is a factor predisposing to acne vulgaris. Szab? K, et al. Tissue Antigens, 2010 Jul 11. PMID 20630038.

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$ 315.00
Cat# AT2513a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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