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IQGAP1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant IQGAP1.

  • WB - IQGAP1 Antibody (monoclonal) (M01) AT2535a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - IQGAP1 Antibody (monoclonal) (M01) AT2535a
    IQGAP1 monoclonal antibody (M01), clone 2C5 Western Blot analysis of IQGAP1 expression in C32 ( (Cat # AT2535a )
  • IHC - IQGAP1 Antibody (monoclonal) (M01) AT2535a
    Immunoperoxidase of monoclonal antibody to IQGAP1 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 1 ug/ml]
  • IF - IQGAP1 Antibody (monoclonal) (M01) AT2535a
    Immunofluorescence of monoclonal antibody to IQGAP1 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - IQGAP1 Antibody (monoclonal) (M01) AT2535a
    Detection limit for recombinant GST tagged IQGAP1 is approximately 3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P46940
Other Accession NM_003870
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 2C5
Calculated MW 189252 Da
Additional Information
Gene ID 8826
Other Names Ras GTPase-activating-like protein IQGAP1, p195, IQGAP1, KIAA0051
Target/Specificity IQGAP1 (NP_003861, 611 a.a. ~ 710 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsIQGAP1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.


Honokiol inhibits HepG2 migration via down-regulation of IQGAP1 expression discovered by a quantitative pharmaceutical proteomic analysis. Liang S, et al. Proteomics, 2010 Apr. PMID 20127691.Endothelial IQGAP1 regulates efficient lymphocyte transendothelial migration. Nakhaei-Nejad M, et al. Eur J Immunol, 2010 Jan. PMID 20017185.Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion. Hayashi H, et al. Int J Cancer, 2010 Jun 1. PMID 19856315.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway. Wang JB, et al. J Cell Sci, 2009 Jun 15. PMID 19454477.

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$ 315.00
Cat# AT2535a
(40 western blots)
Availability: 7-10 days
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