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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ISL1 Antibody (monoclonal) (M01)   

ISL1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant ISL1.

  • WB - ISL1 Antibody (monoclonal) (M01) AT2560a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.41 KDa) .
  • WB - ISL1 Antibody (monoclonal) (M01) AT2560a
    ISL1 monoclonal antibody (M01), clone 1A3. Western Blot analysis of ISL1 expression in Hela S3 NE((Cat # AT2560a )
  • WB - ISL1 Antibody (monoclonal) (M01) AT2560a
    ISL1 monoclonal antibody (M01), clone 1A3. Western Blot analysis of ISL1 expression in K-562((Cat # AT2560a )
  • WB - ISL1 Antibody (monoclonal) (M01) AT2560a
    Western Blot analysis of ISL1 expression in transfected 293T cell line by ISL1 monoclonal antibody (M01), clone 1A3.

    Lane 1: ISL1 transfected lysate(38.7 KDa).
    Lane 2: Non-transfected lysate.
  • E - ISL1 Antibody (monoclonal) (M01) AT2560a
    Detection limit for recombinant GST tagged ISL1 is approximately 30ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P61371
Other Accession NM_002202
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1A3
Calculated MW 39036 Da
Additional Information
Gene ID 3670
Other Names Insulin gene enhancer protein ISL-1, Islet-1, ISL1
Target/Specificity ISL1 (NP_002193, 63 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsISL1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.


New mutations in ZFPM2/FOG2 gene in tetralogy of Fallot and double outlet right ventricle. De Luca A, et al. Clin Genet, 2010 Aug 2. PMID 20807224.Common variation in ISL1 confers genetic susceptibility for human congenital heart disease. Stevens KN, et al. PLoS One, 2010 May 26. PMID 20520780.A Three-Stage Genome-Wide Association Study of General Cognitive Ability: Hunting the Small Effects. Davis OS, et al. Behav Genet, 2010 Mar 21. PMID 20306291.Early first trimester human embryonic cardiac Islet-1 progenitor cells and cardiomyocytes: Immunohistochemical and electrophysiological characterization. Genead R, et al. Stem Cell Res, 2010 Jan. PMID 19896915.The LIM-homeodomain protein ISL1 activates insulin gene promoter directly through synergy with BETA2. Zhang H, et al. J Mol Biol, 2009 Sep 25. PMID 19619559.

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$ 315.00
Cat# AT2560a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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