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ITGA4 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT2564a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ITGA4 Antibody (monoclonal) (M01) - Product info | |
| Application | WB
|
| Primary Accession | P13612 |
| Other Accession | NP_000876 |
| Reactivity | Human |
| Concentration | 1 mg/ml |
| Isotype | IgG1 Kappa |
| Clone Names | 2C11 |
| Calculated MW | 114900 Da |
ITGA4 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 3676 | |
| Other Names CD49D, IA4, MGC90518integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | |
| Target/Specificity ITGA4 (NP_000876, 98 a.a. ~ 208 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ITGA4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ITGA4 Antibody (monoclonal) (M01) - Application data
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ITGA4 monoclonal antibody (M01), clone 2C11 Western Blot analysis of ITGA4 expression in Jurkat ( Cat # L017V1 ).
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Detection limit for recombinant GST tagged ITGA4 is approximately 0.3ng/ml as a capture antibody.
ITGA4 Antibody (monoclonal) (M01) - Related products
RI12780: ITGA4 predesign siRNA
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BACKGROUND
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis. Garmy-Susini B, et al. Cancer Res, 2010 Apr 15. PMID 20388801.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.TAp63 regulates VLA-4 expression and chronic lymphocytic leukemia cell migration to the bone marrow in a CD74-dependent manner. Binsky I, et al. J Immunol, 2010 May 1. PMID 20357260.Multiple common variants for celiac disease influencing immune gene expression. Dubois PC, et al. Nat Genet, 2010 Apr. PMID 20190752.
