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ITGA6 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT2565a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ITGA6 Antibody (monoclonal) (M01) - Product info | |
| Primary Accession | P23229 |
| Other Accession | NP_000201 |
| Reactivity | Human |
| Isotype | IgG2a Kappa |
| Clone Names | 4C1 |
| Calculated MW | 126633 Da |
ITGA6 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 3655 | |
| Other Names CD49fintegrin, alpha 6 | |
| Target/Specificity ITGA6 (NP_000201, 24 a.a. ~ 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ITGA6 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ITGA6 Antibody (monoclonal) (M01) - Related products
AP2753a: ITGA6 Antibody (isoform 2 S1064)
AP3687a: Phospho-ITGA6 iso2-pS1064 Antibody
AP9255b: CD49f Antibody (C-term)
RI12782: ITGA6 predesign siRNA
BP2753a: ITGA6 Antibody (isoform 2 S1064) Blocking Peptide
BP3687a: Phospho-ITGA6 iso2-pS1064 Antibody Blocking Peptide
ITGA6 Antibody (monoclonal) (M01) - Application data
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Detection limit for recombinant GST tagged ITGA6 is approximately 0.1ng/ml as a capture antibody.
ITGA6 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
REFERENCES
Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624.Prostate cancer risk-associated variants reported from genome-wide association studies: Meta-analysis and their contribution to genetic Variation. Kim ST, et al. Prostate, 2010 Jun 16. PMID 20564319.alpha6-integrin subunit plays a major role in the proangiogenic properties of endothelial progenitor cells. Bouvard C, et al. Arterioscler Thromb Vasc Biol, 2010 Aug. PMID 20508204.Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. Wang Y, et al. J Hum Genet, 2010 Aug. PMID 20485444.Usage of heparan sulfate, integrins, and FAK in HPV16 infection. Abban CY, et al. Virology, 2010 Jul 20. PMID 20441998.
