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>   home   >   Products   >   Primary Antibodies   >   JARID1A Antibody (monoclonal) (M03)   

JARID1A Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant JARID1A.

  • WB - JARID1A Antibody (monoclonal) (M03) AT2580a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - JARID1A Antibody (monoclonal) (M03) AT2580a
    Western Blot analysis of JARID1A expression in transfected 293T cell line by JARID1A monoclonal antibody (M03), clone 1H2.

    Lane 1: JARID1A transfected lysate (Predicted MW: 11.11 KDa).
    Lane 2: Non-transfected lysate.
  • E - JARID1A Antibody (monoclonal) (M03) AT2580a
    Detection limit for recombinant GST tagged JARID1A is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P29375
Other Accession NM_005056
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1H2
Calculated MW 192095 Da
Additional Information
Gene ID 5927
Other Names Lysine-specific demethylase 5A, 11411-, Histone demethylase JARID1A, Jumonji/ARID domain-containing protein 1A, Retinoblastoma-binding protein 2, RBBP-2, KDM5A, JARID1A, RBBP2, RBP2
Target/Specificity JARID1A (NP_005047, 191 a.a. ~ 290 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsJARID1A Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein.


Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase. Ge Z, et al. FASEB J, 2010 Feb. PMID 19762557. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Wang GG, et al. Nature, 2009 Jun 11. PMID 19430464. Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation. Lopez-Bigas N, et al. Mol Cell, 2008 Aug 22. PMID 18722178. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348. RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation. Hayakawa T, et al. Genes Cells, 2007 Jun. PMID 17573780.

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$ 315.00
Cat# AT2580a
(40 western blots)
Availability: 7-10 days
Bulk Size
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