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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   JUP Antibody (monoclonal) (M01)   

JUP Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant JUP.

  • WB - JUP Antibody (monoclonal) (M01) AT2587a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (107.69 KDa) .
  • WB - JUP Antibody (monoclonal) (M01) AT2587a
    JUP monoclonal antibody (M01), clone 2G9 Western Blot analysis of JUP expression in A-431 ( (Cat # AT2587a )
  • WB - JUP Antibody (monoclonal) (M01) AT2587a
    Western Blot analysis of JUP expression in transfected 293T cell line by JUP monoclonal antibody (M01), clone 2G9.

    Lane 1: JUP transfected lysate(81.7 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - JUP Antibody (monoclonal) (M01) AT2587a
    Immunoperoxidase of monoclonal antibody to JUP on formalin-fixed paraffin-embedded human lymphoma tissue. [antibody concentration 3 ug/ml]
  • IF - JUP Antibody (monoclonal) (M01) AT2587a
    Immunofluorescence of monoclonal antibody to JUP on A-431 cell. [antibody concentration 10 ug/ml]
  • E - JUP Antibody (monoclonal) (M01) AT2587a
    Detection limit for recombinant GST tagged JUP is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P14923
Other Accession BC011865
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2G9
Calculated MW 81745 Da
Additional Information
Gene ID 3728
Other Names Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3
Target/Specificity JUP (AAH11865.1, 1 a.a. ~ 745 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsJUP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.


Expression of the E-cadherin-catenin complex in patients with pancreatic ductal adenocarcinoma. Pryczynicz A, et al. Folia Histochem Cytobiol, 2010 Jan 1. PMID 20529828. The expression of E-cadherin-catenin complex in patients with advanced gastric cancer: role in formation of metastasis. Czyzewska J, et al. Folia Histochem Cytobiol, 2010 Jan 1. PMID 20529814. Desmosomal gene analysis in arrhythmogenic right ventricular dysplasia/cardiomyopathy: spectrum of mutations and clinical impact in practice. Fressart V, et al. Europace, 2010 Jun. PMID 20400443. Homozygous mutations in the 5' region of the JUP gene result in cutaneous disease but normal heart development in children. Cabral RM, et al. J Invest Dermatol, 2010 Jun. PMID 20130592. Plakoglobin interacts with and increases the protein levels of metastasis suppressor Nm23-H2 and regulates the expression of Nm23-H1. Aktary Z, et al. Oncogene, 2010 Apr 8. PMID 20101217.

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$ 315.00
Cat# AT2587a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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