KIF2C Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant KIF2C.
|Application ||WB, IHC, IF, IP|
|Calculated MW||81313 Da|
|Other Names||Kinesin-like protein KIF2C, Kinesin-like protein 6, Mitotic centromere-associated kinesin, MCAK, KIF2C, KNSL6|
|Target/Specificity||KIF2C (AAH14924, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||KIF2C Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.
1.Mitotic Rounding Alters Cell Geometry to Ensure Efficient Bipolar Spindle Formation.Lancaster OM, Le Berre M, Dimitracopoulos A, Bonazzi D, Zlotek-Zlotkiewicz E, Picone R, Duke T, Piel M, Baum BDev Cell. 2013 May 13;25(3):270-83. doi: 10.1016/j.devcel.2013.03.014. Epub 2013 Apr 25.2.Functional and spatial regulation of the mitotic centromere-associated kinesin by cyclin-dependent kinase 1.Sanhaji M, Friel CT, Kreis NN, Kramer A, Martin C, Howard J, Strebhardt K, Yuan J.Mol Cell Biol. 2010 Apr 5. [Epub ahead of print]
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