KLF13 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant KLF13.
|Reactivity||Human, Mouse, Rat|
|Calculated MW||31180 Da|
|Other Names||Krueppel-like factor 13, Basic transcription element-binding protein 3, BTE-binding protein 3, Novel Sp1-like zinc finger transcription factor 1, RANTES factor of late activated T-lymphocytes 1, RFLAT-1, Transcription factor BTEB3, Transcription factor NSLP1, KLF13, BTEB3, NSLP1|
|Target/Specificity||KLF13 (AAH13946, 31 a.a. ~ 72 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||KLF13 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).
Overexpression of KLF13 and FGFR3 in oral cancer cells. Henson BJ, et al. Cytogenet Genome Res, 2010 Jun. PMID 20539070.Functional differentiation of uterine stromal cells involves cross-regulation between bone morphogenetic protein 2 and Kruppel-like factor (KLF) family members KLF9 and KLF13. Pabona JM, et al. Endocrinology, 2010 Jul. PMID 20410205.Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells. Natesampillai S, et al. Am J Physiol Endocrinol Metab, 2008 Feb. PMID 18056793.Interaction of PRP4 with Kruppel-like factor 13 regulates CCL5 transcription. Huang B, et al. J Immunol, 2007 Jun 1. PMID 17513757.Dynamic interplay of transcriptional machinery and chromatin regulates late expression of the chemokine RANTES in T lymphocytes. Ahn YT, et al. Mol Cell Biol, 2007 Jan. PMID 17074812.
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