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>   home   >   Products   >   Primary Antibodies   >   KLF8 Antibody (monoclonal) (M09)   

KLF8 Antibody (monoclonal) (M09)

Mouse monoclonal antibody raised against a partial recombinant KLF8.

  • WB - KLF8 Antibody (monoclonal) (M09) AT2635a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
  • WB - KLF8 Antibody (monoclonal) (M09) AT2635a
    Western Blot analysis of KLF8 expression in transfected 293T cell line by KLF8 monoclonal antibody (M09), clone 2E10.

    Lane 1: KLF8 transfected lysate(39.3 KDa).
    Lane 2: Non-transfected lysate.
  • E - KLF8 Antibody (monoclonal) (M09) AT2635a
    Detection limit for recombinant GST tagged KLF8 is 3 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95600
Other Accession NM_007250
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2E11
Calculated MW 39314 Da
Additional Information
Gene ID 11279
Other Names Krueppel-like factor 8, Basic krueppel-like factor 3, Zinc finger protein 741, KLF8, BKLF3, ZNF741
Target/Specificity KLF8 (NP_009181.1, 1 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsKLF8 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.


Small interference RNA targeting Kr?ppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo. Fu WJ, et al. J Cancer Res Clin Oncol, 2010 Aug. PMID 20182889.Activation of KLF8 transcription by focal adhesion kinase in human ovarian epithelial and cancer cells. Wang X, et al. J Biol Chem, 2008 May 16. PMID 18353772.Kr?ppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. Wang X, et al. Cancer Res, 2007 Aug 1. PMID 17671186.Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation. Hu JH, et al. J Mol Biol, 2007 Mar 2. PMID 17224162.KLF8 transcription factor participates in oncogenic transformation. Wang X, et al. Oncogene, 2007 Jan 18. PMID 16832343.

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$ 315.00
Cat# AT2635a
(40 western blots)
Availability: 7-10 days
Bulk Size
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