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KLF9 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant KLF9.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q13886 |
| Other Accession | NM_001206 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2B9 |
| Calculated MW | 27235 Da |
| Gene ID | 687 |
|---|---|
| Other Names | Krueppel-like factor 9, Basic transcription element-binding protein 1, BTE-binding protein 1, GC-box-binding protein 1, Transcription factor BTEB1, KLF9, BTEB, BTEB1 |
| Target/Specificity | KLF9 (NP_001197, 25 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | KLF9 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription.
References
Functional differentiation of uterine stromal cells involves cross-regulation between bone morphogenetic protein 2 and Kruppel-like factor (KLF) family members KLF9 and KLF13. Pabona JM, et al. Endocrinology, 2010 Jul. PMID 20410205.GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells. Gamper I, et al. Exp Hematol, 2009 May. PMID 19375645.The Kr?ppel-like factor 9 (KLF9) network in HEC-1-A endometrial carcinoma cells suggests the carcinogenic potential of dys-regulated KLF9 expression. Simmen FA, et al. Reprod Biol Endocrinol, 2008 Sep 10. PMID 18783612.Downregulation of Kr?ppel-like factor 9 in human colorectal cancer. Kang L, et al. Pathol Int, 2008 Jun. PMID 18477211.Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9. Ohguchi H, et al. Mol Cell Biol, 2008 Jun. PMID 18426912.
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