LASS2 Antibody (monoclonal) (M01A)
Mouse monoclonal antibody raised against a full-length recombinant LASS2.
|Calculated MW||44876 Da|
|Other Names||Ceramide synthase 2, CerS2, LAG1 longevity assurance homolog 2, SP260, Tumor metastasis-suppressor gene 1 protein, CERS2, LASS2, TMSG1|
|Target/Specificity||LASS2 (AAH01357, 1 a.a. ~ 380 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||LASS2 Antibody (monoclonal) (M01A) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
1.siRNA-Mediated Down-regulation of Ceramide Synthase 1 Leads to Apoptotic Resistance in Human Head and Neck Squamous Carcinoma Cells after Photodynamic Therapy.Separovic D, Breen P, Joseph N, Bielawski J, Pierce JS, VAN Buren E, Gudz TI.Anticancer Res. 2012 Jul;32(7):2479-85.2.Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.Separovic D, Breen P, Joseph N, Bielawski J, Pierce JS, VAN Buren E, Gudz TI.Anticancer Res. 2012 Mar;32(3):753-60.
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