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LDLR Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant LDLR.

  • WB - LDLR Antibody (monoclonal) (M01) AT2690a
    Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.

    Lane 1: LDLR transfected lysate(94.6 KDa).
    Lane 2: Non-transfected lysate.
  • E - LDLR Antibody (monoclonal) (M01) AT2690a
    Detection limit for recombinant GST tagged LDLR is approximately 0.3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01130
Other Accession NM_000527
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 5E8
Calculated MW 95376 Da
Additional Information
Gene ID 3949
Other Names Low-density lipoprotein receptor, LDL receptor, LDLR
Target/Specificity LDLR (NP_000518, 105 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsLDLR Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.


1.The expression of LDL receptor in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model.Ueno M, Wu B, Nakagawa T, Nagai Y, Onodera M, Huang CL, Kusaka T, Kanenishi K, Sakamoto H.Histochem Cell Biol. 2010 Jun;133(6):669-76. Epub 2010 May 11.

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$ 315.00
Cat# AT2690a
(40 western blots)
Availability: 7-10 days
Bulk Size
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