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LHX1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant LHX1.

     
  • IF - LHX1 Antibody (monoclonal) (M01) AT2705a
    Immunofluorescence of monoclonal antibody to LHX1 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • IHC - LHX1 Antibody (monoclonal) (M01) AT2705a
    Immunoperoxidase of monoclonal antibody to LHX1 on formalin-fixed paraffin-embedded human adrenal gland. [antibody concentration 0.8 ug/ml]
    detail
  • E - LHX1 Antibody (monoclonal) (M01) AT2705a
    Detection limit for recombinant GST tagged LHX1 is approximately 1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, IF, E
Primary Accession P48742
Other Accession NM_005568
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4D1
Calculated MW 44808 Da
Additional Information
Gene ID 3975
Other Names LIM/homeobox protein Lhx1, LIM homeobox protein 1, Homeobox protein Lim-1, hLim-1, LHX1, LIM-1, LIM1
Target/Specificity LHX1 (NP_005559, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsLHX1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of neural and lymphoid cells. A similar protein in mice is an essential regulator of the vertebrate head organizer.

References

The role of genes in the development of Mullerian anomalies: where are we today? Christopoulos P, et al. Obstet Gynecol Surv, 2009 Nov. PMID 19849868.Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1. Avraham O, et al. Neural Dev, 2009 Jun 19. PMID 19545367.Lim1 is essential for the correct laminar positioning of retinal horizontal cells. Poch? RA, et al. J Neurosci, 2007 Dec 19. PMID 18094249.DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. Zody MC, et al. Nature, 2006 Apr 20. PMID 16625196.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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$ 350.00
Cat# AT2705a
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