LHX6 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant LHX6.
|Calculated MW||40045 Da|
|Other Names||LIM/homeobox protein Lhx6, LIM homeobox protein 6, LIM/homeobox protein Lhx61, LHX6, LHX61|
|Target/Specificity||LHX6 (NP_055183, 274 a.a. ~ 363 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||LHX6 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Human variation in alcohol response is influenced by variation in neuronal signaling genes. Joslyn G, et al. Alcohol Clin Exp Res, 2010 May. PMID 20201926.LHX6 is a sensitive methylation marker in head and neck carcinomas. Est?cio MR, et al. Oncogene, 2006 Aug 17. PMID 16732332.The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
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