LSP1 Antibody (monoclonal) (M07)
Mouse monoclonal antibody raised against a partial recombinant LSP1.
|Application ||WB, E|
|Calculated MW||37192 Da|
|Other Names||Lymphocyte-specific protein 1, 47 kDa actin-binding protein, 52 kDa phosphoprotein, pp52, Lymphocyte-specific antigen WP34, LSP1, WP34|
|Target/Specificity||LSP1 (NP_002330.1, 240 a.a. ~ 338 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||LSP1 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study. Travis RC, et al. Lancet, 2010 Jun 19. PMID 20605201.FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women. Barnholtz-Sloan JS, et al. Carcinogenesis, 2010 Aug. PMID 20554749.Genome-wide association study identifies five new breast cancer susceptibility loci. Turnbull C, et al. Nat Genet, 2010 Jun. PMID 20453838.Distribution of FGFR2, TNRC9, MAP3K1, LSP1, and 8q24 alleles in genetically enriched breast cancer patients versus elderly tumor-free women. Gorodnova TV, et al. Cancer Genet Cytogenet, 2010 May. PMID 20417875.
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