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MAD2L1BP Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a full-length recombinant MAD2L1BP.

  • WB - MAD2L1BP Antibody (monoclonal) (M03) AT2759a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (55.88 KDa) .
  • WB - MAD2L1BP Antibody (monoclonal) (M03) AT2759a
    MAD2L1BP monoclonal antibody (M03), clone 4G11. Western Blot analysis of MAD2L1BP expression in Hela S3 NE ( (Cat # AT2759a )
  • IF - MAD2L1BP Antibody (monoclonal) (M03) AT2759a
    Immunofluorescence of monoclonal antibody to MAD2L1BP on HeLa cell . [antibody concentration 10 ug/ml]
  • E - MAD2L1BP Antibody (monoclonal) (M03) AT2759a
    Detection limit for recombinant GST tagged MAD2L1BP is 1 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15013
Other Accession BC002904
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4G11
Calculated MW 31052 Da
Additional Information
Gene ID 9587
Other Names MAD2L1-binding protein, Caught by MAD2 protein, MAD2L1BP, CMT2, KIAA0110
Target/Specificity MAD2L1BP (AAH02904, 1 a.a. ~ 274 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMAD2L1BP Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.


p31comet Induces cellular senescence through p21 accumulation and Mad2 disruption. Yun M, et al. Mol Cancer Res, 2009 Mar. PMID 19276188.An empirical framework for binary interactome mapping. Venkatesan K, et al. Nat Methods, 2009 Jan. PMID 19060904.p31comet blocks Mad2 activation through structural mimicry. Yang M, et al. Cell, 2007 Nov 16. PMID 18022368.Mutation analysis of p31comet gene, a negative regulator of Mad2, in human hepatocellular carcinoma. Yun MY, et al. Exp Mol Med, 2007 Aug 31. PMID 17934339.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.

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$ 315.00
Cat# AT2759a
(40 western blots)
Availability: 7-10 days
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