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MAF Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant MAF.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | O75444 |
| Other Accession | NM_005360 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 6B6 |
| Calculated MW | 38492 Da |
| Gene ID | 4094 |
|---|---|
| Other Names | Transcription factor Maf, Proto-oncogene c-Maf, V-maf musculoaponeurotic fibrosarcoma oncogene homolog, MAF |
| Target/Specificity | MAF (NP_005351, 304 a.a. ~ 403 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MAF Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.
References
Genetic variants that affect length/height in infancy/early childhood in Vietnamese-Korean families. Kim HN, et al. J Hum Genet, 2010 Jul 29. PMID 20668459.Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. Fontaine-Bisson B, et al. Diabetologia, 2010 Oct. PMID 20571754.SUMOylation attenuates c-Maf-dependent IL-4 expression. Lin BS, et al. Eur J Immunol, 2010 Apr. PMID 20127678.KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. Hansen A, et al. Genes Dev, 2010 Jan 15. PMID 20080955.Transcriptional activation of human MMP-13 gene expression by c-Maf in osteoarthritic chondrocyte. Li T, et al. Connect Tissue Res, 2010. PMID 20067416.
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