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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MAPK6 Antibody (monoclonal) (M02)   

MAPK6 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant MAPK6.

  • WB - MAPK6 Antibody (monoclonal) (M02) AT2792a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - MAPK6 Antibody (monoclonal) (M02) AT2792a
    MAPK6 monoclonal antibody (M02), clone 4C11. Western Blot analysis of MAPK6 expression in PC-12((Cat # AT2792a )
  • WB - MAPK6 Antibody (monoclonal) (M02) AT2792a
    MAPK6 monoclonal antibody (M02), clone 4C11. Western Blot analysis of MAPK6 expression in Raw 264.7((Cat # AT2792a )
  • WB - MAPK6 Antibody (monoclonal) (M02) AT2792a
    MAPK6 monoclonal antibody (M02), clone 4C11 Western Blot analysis of MAPK6 expression in Jurkat ( (Cat # AT2792a )
  • IF - MAPK6 Antibody (monoclonal) (M02) AT2792a
    Immunofluorescence of monoclonal antibody to MAPK6 on HeLa cell. [antibody concentration 10 ug/ml]
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16659
Other Accession BC035492
Reactivity Human, Mouse, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 4C11
Calculated MW 82681 Da
Additional Information
Gene ID 5597
Other Names Mitogen-activated protein kinase 6, MAP kinase 6, MAPK 6, Extracellular signal-regulated kinase 3, ERK-3, MAP kinase isoform p97, p97-MAPK, MAPK6, ERK3, PRKM6
Target/Specificity MAPK6 (AAH35492, 612 a.a. ~ 721 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMAPK6 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.


Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. D?l?ris P, et al. J Cell Physiol, 2008 Dec. PMID 18720373.Regulation of ERK3/MAPK6 expression by BRAF. Hoeflich KP, et al. Int J Oncol, 2006 Oct. PMID 16964379.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome. Coulombe P, et al. Mol Cell Biol, 2004 Jul. PMID 15226418.

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$ 315.00
Cat# AT2792a
(40 western blots)
Availability: 7-10 days
Bulk Size
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