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MBNL1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant MBNL1.

     
  • WB - MBNL1 Antibody (monoclonal) (M01) AT2813a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (63.47 KDa) .
    detail
  • WB - MBNL1 Antibody (monoclonal) (M01) AT2813a
    MBNL1 monoclonal antibody (M01), clone 1D11 Western Blot analysis of MBNL1 expression in Hela S3 NE ( (Cat # AT2813a )
    detail
  • E - MBNL1 Antibody (monoclonal) (M01) AT2813a
    Detection limit for recombinant GST tagged MBNL1 is 0.1 ng/ml as a capture antibody.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NR56
Other Accession BC050535
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1D11
Calculated MW 41817 Da
Additional Information
Gene ID 4154
Other Names Muscleblind-like protein 1, Triplet-expansion RNA-binding protein, MBNL1, EXP, KIAA0428, MBNL
Target/Specificity MBNL1 (AAH50535, 1 a.a. ~ 343 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMBNL1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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References

Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer. Sen S, et al. J Biol Chem, 2010 Aug 13. PMID 20519504.A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding. Arambula JF, et al. Proc Natl Acad Sci U S A, 2009 Sep 22. PMID 19805260.Ribonuclear inclusions and MBNL1 nuclear sequestration do not affect myoblast differentiation but alter gene splicing in myotonic dystrophy type 2. Cardani R, et al. Neuromuscul Disord, 2009 May. PMID 19345584.Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle. Holt I, et al. Am J Pathol, 2009 Jan. PMID 19095965.Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1. Teplova M, et al. Nat Struct Mol Biol, 2008 Dec. PMID 19043415.

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$ 350.00
Cat# AT2813a
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