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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ME1 Antibody (monoclonal) (M02)   

ME1 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full length recombinant ME1.

  • WB - ME1 Antibody (monoclonal) (M02) AT2829a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (88.66 KDa) .
  • E - ME1 Antibody (monoclonal) (M02) AT2829a
    Detection limit for recombinant GST tagged ME1 is approximately 3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48163
Other Accession BC025246
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 3B4
Calculated MW 64150 Da
Additional Information
Gene ID 4199
Other Names NADP-dependent malic enzyme, NADP-ME, Malic enzyme 1, ME1
Target/Specificity ME1 (AAH25246, 1 a.a. ~ 572 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsME1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.


Long-range interaction between the enzyme active site and a distant allosteric site in the human mitochondrial NAD(P)+-dependent malic enzyme. Hsieh JY, et al. Arch Biochem Biophys, 2009 Jul 1. PMID 19464998.Functional roles of the tetramer organization of malic enzyme. Hsieh JY, et al. J Biol Chem, 2009 Jul 3. PMID 19416979.Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion. Heart E, et al. Am J Physiol Endocrinol Metab, 2009 Jun. PMID 19293334.Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. Lu Y, et al. J Lipid Res, 2008 Dec. PMID 18660489.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.

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$ 315.00
Cat# AT2829a
(40 western blots)
Availability: 7-10 days
Bulk Size
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