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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MEFV Antibody (monoclonal) (M01)   

MEFV Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MEFV.

  • WB - MEFV Antibody (monoclonal) (M01) AT2840a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • E - MEFV Antibody (monoclonal) (M01) AT2840a
    Detection limit for recombinant GST tagged MEFV is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15553
Other Accession NM_000243
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4E7
Calculated MW 86444 Da
Additional Information
Gene ID 4210
Other Names Pyrin, Marenostrin, MEFV, MEF
Target/Specificity MEFV (NP_000234, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMEFV Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.


An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.Association of familial mediterranean fever-related MEFV gene variations with ankylosing spondylitis. Cosan F, et al. Arthritis Rheum, 2010 Jul 28. PMID 20669279.Mediterranean fever (MEFV) gene mutation frequency is not increased in adults with rheumatic heart disease. Simsek I, et al. Clin Rheumatol, 2010 Jul 20. PMID 20645115.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.MEFV E148Q polymorphism is associated with Henoch-Sch?nlein purpura in Chinese children. He X, et al. Pediatr Nephrol, 2010 Oct. PMID 20602240.

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$ 315.00
Cat# AT2840a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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