MGRN1 Antibody (monoclonal) (M07)
Mouse monoclonal antibody raised against a partial recombinant MGRN1.
|Application ||WB, IF|
|Calculated MW||60753 Da|
|Other Names||E3 ubiquitin-protein ligase MGRN1, 632-, Mahogunin RING finger protein 1, RING finger protein 156, MGRN1, KIAA0544, RNF156|
|Target/Specificity||MGRN1 (NP_056061, 477 a.a. ~ 576 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||MGRN1 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas. P?rez-Oliva AB, et al. J Biol Chem, 2009 Nov 13. PMID 19737927.Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration. Chakrabarti O, et al. Cell, 2009 Jun 12. PMID 19524515.Pigmentation-related genes and their implication in malignant melanoma susceptibility. Fernandez LP, et al. Exp Dermatol, 2009 Jul. PMID 19320733.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
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