MKNK1 Antibody (monoclonal) (M14)
Mouse monoclonal antibody raised against a full length recombinant MKNK1.
|Application ||WB, IHC, IF|
|Calculated MW||51342 Da|
|Other Names||MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1, MKNK1, MNK1|
|Target/Specificity||MKNK1 (AAH02755.1, 1 a.a. ~ 465 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||MKNK1 Antibody (monoclonal) (M14) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.The C-terminal domain of Mnk1a plays a dual role in tightly regulating its activity. Goto S, et al. Biochem J, 2009 Sep 25. PMID 19650764.Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation. Wang X, et al. Mol Cell Biol, 2007 Nov. PMID 17724079.Characterization of the activity of human MAP kinase-interacting kinase Mnk1b. O'Loghlen A, et al. Biochim Biophys Acta, 2007 Sep. PMID 17590453.Elevated inorganic phosphate stimulates Akt-ERK1/2-Mnk1 signaling in human lung cells. Chang SH, et al. Am J Respir Cell Mol Biol, 2006 Nov. PMID 16763222.
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