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MMP28 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant MMP28.

     
  • WB - MMP28 Antibody (monoclonal) (M01) AT2882a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.54 KDa) .
    detail
  • E - MMP28 Antibody (monoclonal) (M01) AT2882a
    Detection limit for recombinant GST tagged MMP28 is 0.03 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9H239
Other Accession NM_024302
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3C11
Calculated MW 58939 Da
Additional Information
Gene ID 79148
Other Names Matrix metalloproteinase-28, MMP-28, 3424-, Epilysin, MMP28, MMP25
Target/Specificity MMP28 (NP_077278, 441 a.a. ~ 520 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsMMP28 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described.

References

MMP28 gene expression is regulated by Sp1 transcription factor acetylation. Swingler TE, et al. Biochem J, 2010 Apr 14. PMID 20144149.Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs. Gruber HE, et al. Arthritis Res Ther, 2009. PMID 20003223.Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma. Suomela S, et al. Virchows Arch, 2009 Dec. PMID 19921252.Epilysin (MMP-28) is deposited to the basolateral extracellular matrix of epithelial cells. Heiskanen TJ, et al. Matrix Biol, 2009 Mar. PMID 19379669.Expression and function of matrix metalloproteinase (MMP)-28. Rodgers UR, et al. Matrix Biol, 2009 Jun. PMID 19375502.

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$ 350.00
Cat# AT2882a
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